منابع مشابه
Mass dedifferentiation
he machine that is a cell is more than the sum of its protein parts. A large step toward understanding how those parts are so effectively put together has been taken by Patrick Aloy, Rob Russell (EMBL, Heidelberg, Germany), and colleagues. Their work has identified ف 100 yeast protein complexes and predicted interactions within and among many of them. " We were working on a large scale to mod...
متن کاملLipid extrusion during dedifferentiation
Clonal cultures of pig-derived mature adipocytes are capable of dedifferentiating and forming proliferative-competent progeny cells in vitro. Initial lipid processing, is different to that observed in cultures of beef-derived adipocytes. Mature pig adipocytes extrude lipid before proliferation, whereas beef-derived adipocytes symmetrically, or asymmetrically, divide without expelling lipid. The...
متن کاملExplorer Dopamine and memory dedifferentiation in aging
1 The dedifferentiation theory of aging proposes that a reduction in the specificity of neural 2 representations causes declines in complex cognition as people get older, and may reflect a 3 reduction in dopaminergic signaling. The present pharmacological fMRI study investigated episodic 4 memory-related dedifferentiation in young and older adults, and its relation to dopaminergic 5 function, u...
متن کاملSkeletal muscle dedifferentiation during salamander limb regeneration.
Salamanders can regenerate entire limbs throughout their life. A critical step during limb regeneration is formation of a blastema, which gives rise to the new extremity. Salamander limb regeneration has historically been tightly linked to the term dedifferentiation, however, with refined research tools it is important to revisit the definition of dedifferentiation in the context. To what exten...
متن کاملDedifferentiation and Proliferation of Mammalian Cardiomyocytes
BACKGROUND It has long been thought that mammalian cardiomyocytes are terminally-differentiated and unable to proliferate. However, myocytes in more primitive animals such as zebrafish are able to dedifferentiate and proliferate to regenerate amputated cardiac muscle. METHODOLOGY/PRINCIPAL FINDINGS Here we test the hypothesis that mature mammalian cardiomyocytes retain substantial cellular pl...
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ژورنال
عنوان ژورنال: Plants
سال: 2015
ISSN: 2223-7747
DOI: 10.3390/plants4030356